Bioavailability of vitamin E stereoisomers

Synthetic vitamin E consists of an equi-molar mixture of eight stereoisomers (RRR -, RRS, RSR, RSS, SRR, SRS, SSR, SSSa – tocopherol stereoisomers) . Not all of these stereoisomers are equally bio-available. Yueming Dersjant-Li and Manfred Peisker explain why this is.                       In general, 2R forms (RRR, RRS, RSR, RSS, i.e. R configuration at position 2 of the side chain) are bio-available and 2S forms (SSS-, SRS-, S